Industry Research – Genes to Genomes https://genestogenomes.org A blog from the Genetics Society of America Tue, 29 Oct 2024 17:22:51 +0000 en-US hourly 1 https://wordpress.org/?v=6.6.2 https://genestogenomes.org/wp-content/uploads/2023/06/cropped-G2G_favicon-32x32.png Industry Research – Genes to Genomes https://genestogenomes.org 32 32 Early Career Leadership Spotlight: Olufemi Osonowo https://genestogenomes.org/early-career-leadership-spotlight-olufemi-osonowo/ Thu, 07 Nov 2024 18:00:00 +0000 https://genestogenomes.org/?p=87509 We’re taking time to get to know the members of the GSA’s Early Career Scientist Committees. Join us to learn more about our early career scientist advocates.

Olufemi Adekunle Osonowo
Career Development Subcommittee
Dalhousie University

Research Interest

Metabolomics and genomics are two distinct but complimentary approaches that offer valuable insights into the underlying mechanisms of complex traits, such as feed efficiency in sheep. My current research, which involves sustainable livestock production and the application of bioinformatics and machine learning to livestock production, seeks to unlock those insights.

In addition, I seek to develop a standardized operational procedure for optimizing the feed intake test period to use limited test station facilities more efficiently and accelerate selection rate by testing more animals in sheep production. Through genomic signature selection, both metabolomics and genomics will enable the measurement and association of metabolites in sheep that are linked with feed efficiency while also identifying specific genetic biomarkers associated with feed efficiency in sheep.

As a PhD-trained scientist, you have many career options. What interests you the most?

As an MSc student, I have multifaceted interests, encompassing both academic and applied aspects of science. My primary focus is sustainable livestock production, where I aim to improve efficiency and productivity while minimizing environmental impact. This interest aligns with the growing global demand for sustainable agricultural practices and the necessity to feed an increasing population.

One of the most intriguing areas for me is the application of bioinformatics and machine learning to livestock production. These cutting-edge technologies offer immense potential to revolutionize traditional agricultural practices. By analyzing large datasets, we can uncover patterns and insights that were previously inaccessible, leading to significant advancements in animal breeding, disease management, and overall farm management. For instance, genomics and metabolomics data can be used to identify biomarkers for disease resistance or superior production traits, enabling more precise and efficient breeding programs.

Machine-learning algorithms can predict and optimize various aspects of livestock management, from feed efficiency to animal health monitoring. The integration of sensor data, environmental factors, and historical performance records into predictive models can help farmers make informed decisions, ultimately leading to more sustainable and profitable operations.

In addition to the technical aspects, I am also passionate about the translational impact of my research. I believe that bridging the gap between scientific discoveries and practical applications is crucial for advancing the field. This connection involves collaborating with industry partners, policymakers, and other stakeholders to ensure that innovative solutions are effectively implemented and adopted.

Moreover, I am interested in the educational and mentorship aspects of my career. As a scientist, I feel a strong responsibility to contribute to the development of the next generation of researchers through activities such as teaching, supervising undergraduate students, and participating in outreach activities to promote scientific literacy and enthusiasm among young people.

I am driven by the potential to impact both the scientific community and the agricultural industry. My goal is to contribute to a future where agricultural practices are more efficient, sustainable, and capable of meeting global food demands while fostering scientific curiosity and innovation in others.

In addition to your research, how do you want to advance the scientific enterprise?

By bridging gaps between different fields, we can develop innovative solutions to complex problems. In my work, I actively seek collaborations with experts in bioinformatics, machine learning, veterinary medicine, and environmental science. This interdisciplinary approach not only enriches my research but also opens new avenues for discovery and application. I aim to foster a culture of collaboration in the scientific community, encouraging researchers to look beyond their disciplines and work together to tackle global challenges.

Furthermore, researchers must be able to convey their findings to diverse audiences, including policymakers, industry stakeholders, and the public. I am committed to improving my own communication skills and helping others do the same. This outreach involves not only publishing in scientific journals but also engaging industry partners, writing for popular science platforms, and participating in science communication workshops. By making scientific knowledge more accessible, we can inspire public interest in science and inform evidence-based decision-making.

In addition, different perspectives and experiences can lead to unique insights and innovative approaches. I am dedicated to promoting diversity in all its forms within the scientific enterprise—e.g., mentoring underrepresented students, advocating for inclusive policies, and participating in initiatives that support diversity in STEM fields. By creating an environment where everyone feels valued and supported, we can ensure that the best ideas and talents are brought to the forefront.

Advancing the scientific enterprise requires a multifaceted approach that goes beyond individual research endeavors. These initiatives not only enhance the quality and reach of scientific research but also ensure that science continues to serve society effectively.

As a leader within the Genetics Society of America, what do you hope to accomplish?

As a leader within GSA, I aim to foster innovation, promote inclusivity, enhance professional development, and advocate for science policy. By addressing these areas, I seek to strengthen the GSA community and make a meaningful impact on the field of genetics.

Innovation is at the heart of scientific progress. As a leader, I want to create an environment that encourages creative thinking and novel approaches to genetic research. Thus, by organizing symposiums, workshops, and conferences for collaborative brainstorming and interdisciplinary exchange, we can drive forward the frontiers of genetic science.

Additionally, a diverse and inclusive community is essential for the health and vibrancy of any scientific organization. I am committed to promoting inclusivity within GSA by championing programs and initiatives that support underrepresented groups in genetics—e.g., mentorship programs, scholarships, and networking opportunities. By fostering a culture of inclusivity, we can ensure that all voices are heard and valued, leading to a richer and more dynamic scientific community. Also, supporting the professional growth of GSA members is a key priority. Planning professional development resources—including career workshops, training sessions, and mentorship programs—will help members at all career stages to develop essential skills, navigate career transitions, and achieve their professional goals. Investing in the professional development of our members helps us cultivate the next generation of leaders in genetics.

I aim to advocate for policies that support funding for genetic research, promote science education, and ensure the ethical use of genetic information. Doing so involves engaging with policymakers, contributing to public discussions, and collaborating with other scientific organizations to amplify our voice. By advocating for supportive policies, we can create a favorable environment for genetic research and its beneficial impacts on society.

Overall, a strong and connected community is fundamental to GSA’s success. I will work to enhance member engagement and communication through regular updates, interactive platforms, and community-building events. By fostering a sense of belonging and shared purpose, we can strengthen the bonds within our society and create a supportive network for all members. We can make significant strides in advancing the field of genetics and addressing the complex challenges of our time.

Previous leadership experience

  • Communication Officer, Dalhousie Agricultural Association of Graduate Students, May 2024-Present
  • Globalink Mentor, Mitacs, April 2024-Present
  • President, National Youth Service Corp; Sustainable Development Goals (SDGs) Community Development Service, August 2019-July 2020
  • Intern (Team Lead), Community-Based Farming Scheme, September 2016- July 2017
  • Editor-in-Chief, The Source Magazine of Nigeria Association of Agricultural Students, Federal University of Agriculture, Abeokuta, November 2015-September 2016
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Why building a network is key for early career scientists https://genestogenomes.org/why-building-a-network-is-key-for-early-career-scientists/ Thu, 19 Sep 2024 14:49:14 +0000 https://genestogenomes.org/?p=87435 Anthony (Tony) Patelunas is an Early Career Leadership Program alum who served as co-chair of the Early Career Scientist Career Development Subcommittee during his time in the program.   The ECLP, which is currently accepting applications, teaches early career scientists leadership, writing, and networking skills, among other important tools that can be applied to careers in…]]>

Anthony (Tony) Patelunas is an Early Career Leadership Program alum who served as co-chair of the Early Career Scientist Career Development Subcommittee during his time in the program.  

The ECLP, which is currently accepting applications, teaches early career scientists leadership, writing, and networking skills, among other important tools that can be applied to careers in academia and industry. 

Tony gained many essential skills through his participation in the ECLP but one particular lesson stands out to him, “The most important skill I gained is learning to proactively manage my own career,” he shared. Through many conversations with mid- and senior-level professionals who started their careers from a similar place and pursued graduate studies in genetics, Tony was able to create a mental picture of how different careers progress, and envision what he wanted his own career journey to look like. “Spoiler: It’s often unexpected and serendipitous!” he pointed out. He started planning for the next two, five, and 10 years and was more intentional in considering and planning his own skill development and the positions he was willing to accept. 

Through the ECLP, Tony made connections that he maintains until today–his new network supports his decision-making as he consults these trusted colleagues before making big career moves. “The combination of a strong network and the opportunity to build skills and experiences beyond my research environment was irreplaceable to my success afterward,” he explained. 

As he continues to plan his career journey over the next couple of years, Tony hopes to pursue committee work and eventually a Board position with GSA and other professional societies. “The ECLP and the ECS Career Development Subcommittee highlighted the importance of building a strong network in my professional community, and the value of early leadership experience for long-term growth,” he shared. Tony sees serving on committees as another opportunity to continue building and expanding one’s network through regular interactions with individuals sharing a common mission. He also sees this as a chance to develop strategic thinking skills which are key to the growth of an organization, as well as an individual and their career. 

Like Tony, many in the ECLP chose to pursue a career in industry, while others have moved on to positions in academia. Through growing their network and skillset, participants can thrive in whatever career path they choose to take. Apply to the Early Career Leadership Program to gain the skills that will help you succeed as well. 

Applications are due October 16, 2024.

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Cracking the pear genome: how students helped unlock a new tool for the pear industry https://genestogenomes.org/cracking-the-pear-genome-how-students-helped-unlock-a-new-tool-for-the-pear-industry/ Wed, 27 Mar 2024 19:17:40 +0000 https://genestogenomes.org/?p=86892 Pears are big business in the United States’ Pacific Northwest. But did you know that traditional pear breeding has remained largely unchanged for centuries? This slow process is difficult and costly, requiring the long-term commitment of labor, materials, and land-space resources. However, traditional pear breeding might get some help from genomics, thanks to a unique…]]>

Pears are big business in the United States’ Pacific Northwest. But did you know that traditional pear breeding has remained largely unchanged for centuries? This slow process is difficult and costly, requiring the long-term commitment of labor, materials, and land-space resources. However, traditional pear breeding might get some help from genomics, thanks to a unique collaboration between students, scientists, and the pear industry fostered through an initiative called the American Campus Tree Genomes (ACTG) Project.

ACTG was born from two professors’ desire to memorialize Auburn University’s iconic Toomer’s Oak trees that were poisoned during the 2010 Auburn University football season. Their plan: sequence the oak’s DNA and create the first-ever live-oak reference genome. To sweeten the pot, they decided to create a semester-long course so that actual Auburn students could take part in sequencing the Auburn oak trees.

“ACTG leverages iconic and economically valuable trees to bridge the gap between students and cutting-edge genomics,” says ACTG co-founder Alex Harkess, PhD. “Students collaboratively assemble, analyze, and publish tree genomes in prestigious journals, gaining invaluable experience.”

The first semester was a success despite most of the students having never written a manuscript, performed command line bioinformatics, or engaged in plant genomics molecular work. It sparked a nationwide initiative, which was officially founded in 2021 by Alex Harkess, PhD, Faculty Investigator at HudsonAlpha Institute for Biotechnology, and Les Goertzen, PhD, Director of the John D. Freeman Herbarium at Auburn University. Other institutions can replicate the experience using their own campus trees as a springboard for scientific and educational endeavors.

ACTG is disrupting traditional academic models, offering students a unique entry point into the world of genomic research. The initiative transcends textbook learning, immersing participants in the actual process of assembling, analyzing, and publishing tree genomes in esteemed scientific journals. Students in this course have access to cutting-edge genome sequencing techniques and bioinformatic skills through experts at HudsonAlpha. By working on genuine research projects with tangible outcomes, students gain confidence and experience, shaping their trajectories toward successful careers in the ever-evolving field of genomics.

“This course is a welcoming opportunity for students and trainees to not just interact with a completely new idea but become proficient in it no matter their skill level. I had no previous experience with bioinformatics, and I came out with an entirely new, highly marketable skill set,” says Harrison Estes, an Auburn University ‘23 grad who participated in the pear genome class. He is currently a graduate student at the University of Wisconsin and credits the ACTG class as helping him achieve this goal.

The emphasis on student participation extends beyond technical training. ACTG actively addresses barriers to STEM entry and persistence, providing valuable opportunities for individuals without access to advanced technologies. The ACTG team seeks out participation from small universities and colleges, community and junior colleges, and HBCUs that lack mature genetics and bioinformatics training pipelines.

The transformative power of ACTG goes beyond equipping students with invaluable skills and experience. By delving into real-world research projects, ACTG participants translate their knowledge into tangible applications that directly benefit the scientific community and economically important industries.

In the case of the pear industry, a cohort of Auburn students in the ACTG initiative worked with pear experts at Washington State University and the USDA Agricultural Research Service to create a high-quality pear genome. The meticulous work of the ACTG students yielded a fully phased, chromosome-scale assembly, a significant advancement over previous efforts.

The d’anjou genome assembly, recently published as a featured article in G3: Genes|Genomes|Genetics, reveals thousands of genomic variants which are of great importance to pear breeding efforts. This high-quality resource unlocks a treasure trove of information for pear breeders. The new genome assembly is also an important tool for studies on the evolution, domestication, and molecular breeding of pear.

“The ACTG: American Campus Tree Genomes program not only built high-quality genomic resources for a valuable pear cultivar that will ultimately benefit growers and consumers alike, but it educated nearly 20 students and scientists in the needs of the apple and pear industry,” said Ines Hanrahan, PhD, Executive Director, Washington Tree Fruit Research Commission.

The pear is only one of many important tree species in the ACTG pipeline. Learn more about the American Campus Tree Genomes project here.

References

  • A chromosome-scale assembly for ‘d’Anjou’ pear
    Alan Yocca, Mary Akinyuwa, Nick Bailey, Brannan Cliver, Harrison Estes, Abigail Guillemette, Omar Hasannin, Jennifer Hutchison, Wren Jenkins, Ishveen Kaur, Risheek Rahul Khanna, Madelene Loftin, Lauren Lopes, Erika Moore-Pollard, Oluwakemisola Olofintila, Gideon Oluwaseye Oyebode, Jinesh Patel, Parbati Thapa, Martin Waldinger, Jie Zhang, Qiong Zhang, Leslie Goertzen, Sarah B Carey, Heidi Hargarten, James Mattheis, Huiting Zhang, Teresa Jones, LoriBeth Boston, Jane Grimwood, Stephen Ficklin, Loren Honaas, Alex Harkess
    G3 Genes|Genomes|Genetics. March 2024. 14(3).
    DOI: 10.1093/g3journal/jkae003

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The Spanish Multilingual Seminar: Challenges of communicating science as Spanish speakers https://genestogenomes.org/the-spanish-multilingual-seminar/ Fri, 11 Nov 2022 21:32:53 +0000 https://genestogenomes.org/?p=83209 Carla Bautista Rodriguez is a PhD candidate in evolutionary biology at Laval University (Canada) and a member of the Genetics Society of America. She is also passionate about outreach and scientific communication. She is an active member of various American and Spanish societies that are dedicated to bringing science to the general public. The GSA…]]>

Carla Bautista Rodriguez is a PhD candidate in evolutionary biology at Laval University (Canada) and a member of the Genetics Society of America. She is also passionate about outreach and scientific communication. She is an active member of various American and Spanish societies that are dedicated to bringing science to the general public.


The GSA multilingual seminar in Spanish, titled “Challenges of Doing and Communicating Science as Spanish Speakers,” was held on September 3, 2021. As revealed by the participant survey conducted during registration, the participants’ origins were very diverse, including many non-Spanish-speaking countries, which indicated the active participation of professionals working in their non-native tongue. Among the outstanding areas of expertise of the participants were pharmaceuticals, agriculture, government jobs, education, and research. This wide range of topics ensured a very fruitful seminar.

The need to meet

This survey revealed shocking perspectives on Spanish speakers in the field of science. While 50 percent of respondents claimed to have an advanced level of English, more than 75 percent admitted to feeling afraid or ashamed when expressing themselves in their professional field. Despite these concerns, more than 80 percent of participants reported making presentations in other languages, and more than 50 percent reported staying abroad. Most respondents also expressed interest in finding a job in countries where their mother tongue is not spoken.

Our panelists

The Spanish seminar was led by 3 incredible panelists with very diverse and interesting profiles. With a more industry-oriented profile, Roberto Carballido is a talent scout and defender of diversity who works for Eli Lilly and Company. A professor at the State University of New York at Buffalo, Javier Blanco is a renowned researcher in the fields of biochemistry and pharmaceutical sciences. And finally, with a biochemical background, Attabey Rodríguez Benítez is as an important science popularizer and editor of SciShow, a YouTube channel.

Challenges as Spanish speakers

We should normalize the experience of not being understood when we arrive in a new country. Consistency and practice are key. After years of dedication to learning a language, feeling disappointed when you do not achieve fluency in practice is normal. In addition, we have to consider the cultural shock of experiencing all these feelings alone, without the support of family and friends. Furthermore, researchers face constant pressure due to the highly competitive and demanding research environment. Therefore, finding a secure network where you feel comfortable is crucial. 

Practical strategies for overcoming the English language barrier

As part of the seminar, we collected great tips from our panelists on speaking and interacting in English:

  1. Outreach is a good way to learn English because you have to explain difficult concepts in an easy way.
  2. If you feel that the language barrier is endless in the first instances of your scientific journey, look for other ways to communicate. Your skills can be displayed in many ways: scripts, graphs, techniques, new methods, etc.
  3. Find a community where you feel safe. The scientific community is likely multicultural in any country. You will interact with many people who are probably going through the same difficulties as you.
  4. Because of #3, native English scientists are used to many different accents, errors, vocabulary, etc. Accept that your accent is not native but still perfect. Your accent is what it is, and it’s nice because it’s a mixture of your native culture and your new culture. Enjoy that distinction! Do not be afraid! Stop looking for perfection. The important thing is to communicate effectively.
  5. If you feel that someone does not understand you, ask: have you understood me? Likewise, when you do not understand, ask your interlocutor to repeat and speak more slowly.
  6. There are many people who want to help, but they will not help you if you do not raise your hand. They won’t read your mind. Ask For Help. You will be surprised by how they help you.
  7. Use tools that make your day-to-day life easier—for example, Grammarly and Wordtune, which are web browser extensions that help correct your texts. (I’m currently using them as I write!)

Why should we continue speaking in Spanish about science?

Transmitting and communicating what we do in our native language is important. English-speaking children are more likely to become passionate about science because they have been exposed to more scientific content in English, the most used scientific language. We, therefore, have to end this bias! We need more resources in Spanish to create scientific interest among young Spanish speakers. The only ones who can do it are scientific Spanish speakers because they can translate science. Furthermore, during the pandemic, there was a growing need and demand from the general population for tools that would allow them to understand what was happening. Let’s take advantage of this opportunity and inform the public about our findings. 

Model your professional career from now on

Finally, we had a conversation more oriented to each participant’s area of expertise, where they shared valuable advice and resources (Table 1). We hope you find all of this information useful, and we especially hope to see you at future GSA seminars! (You can rewatch the webinar here.)

Table 1. Advice and Resources Oriented to Each Area: Outreach, Industry, and Academy.

Notes:

  1. a. https://college.uchicago.edu/academics/science-communications-courses
    b. https://libguides.ncl.ac.uk/sciencecommunication
  2. https://www.aaas.org/programs/mass-media-fellowship
  3. a. https://genetics-gsa.org/career-development/early-career-leadership/
    b. https://elifesciences.org/inside-elife/bd8565f0/elife-ambassadors-an-invitation-to-take-part-in-2022
    c. https://www.ascb.org/associated_committee/postdoc-graduate-student-compass-committee/
    d. https://www.aquinoscuidamos.org/
  4. https://www.linkedin.com
  5. https://www.sacnas.org/
  6. http://jobsontoast.com/how-to-convert-a-scientific-cv-into-a-business-cv/
  7. a. https://app.grammarly.com/
    b. https://www.wordtune.com/
  8. https://getpocket.com/es/

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What you’ll get from TAGC’s Industry Sessions https://genestogenomes.org/what-youll-get-from-tagcs-industry-sessions/ Fri, 08 Nov 2019 18:49:03 +0000 https://genestogenomes.org/?p=62266 Students, postdocs, academic faculty, and industry researchers will all find benefits at the new Industry Sessions at TAGC, to be held April 22–26 2020 in the Washington DC region. When industry scientists and academic labs collaborate, both society and science benefit. That’s one of two big-picture messages Kailene Simon hopes will be conveyed through a…]]>

Students, postdocs, academic faculty, and industry researchers will all find benefits at the new Industry Sessions at TAGC, to be held April 22–26 2020 in the Washington DC region.


When industry scientists and academic labs collaborate, both society and science benefit.

That’s one of two big-picture messages Kailene Simon hopes will be conveyed through a new series of sessions to be held at The Allied Genetics Conference (TAGC) in 2020. The other? “You can do exciting, creative science in an industry setting!” says Simon, a senior scientist with the Rare and Neurologic Diseases Group at Sanofi.

Simon is working closely on developing the Industry Sessions with Mark Johnston, who is a professor at the University of Colorado School of Medicine and the Editor in Chief of GENETICS.

The sessions were originally proposed to meet the needs of GSA’s early career members. “Students and postdocs keep telling us they are interested in careers in industry but don’t know where to start,” says Johnston. “We wanted to help remove some of the mystery.”

But although there is a strong career element to the initiative (there is a recruitment event and an industry career session) the overall focus is on the science. At the “The Biotech Pipeline,” scientists will present on research that has moved from an academic setting to eventual clinical translation. In “Genetic Technology in Agriculture,” researchers will discuss their work improving crops and livestock through genetics. “There have been terrific advances in these areas in recent years that we think attendees will enjoy learning about,” says Johnston. At the Careers in Industry session, Simon will present on transitioning to a biotech career and will interview a range of industry scientists about their experiences.

Both Simon and Johnston hope the sessions will seed industry-academia collaborations.

“We can’t do our job without academic science,” says Simon. “Everything we do is built on the foundation of basic science.” Although industry labs typically have plenty of resources, she says, they don’t often have the luxury of time to explore new research avenues. That’s why industry researchers attend conferences like TAGC, where there are so many new ideas hatching and where they can build relationships with researchers working at the limits of the field. They also get to meet and recruit talented early career researchers into their labs.

The exchange is not one-sided. Academic researchers who spend their careers chasing down new ideas and projects lack the infrastructure to see their ideas applied in the clinic or marketplace. It is quite common, says Simon, for academic labs to receive funds from industry labs, thus establishing a collaboration with the common goal of clinical application. This allows the academic lab to “keep doing what they’re doing,” i.e. pursuing discovery research and building knowledge. Collaborating with industry can provide academic labs with not only funds, but translational expertise, access to clinical or field samples, and the institutional machinery for bringing an idea through development and approval to market.

“Genetics has so much potential for clinical application, I think it’s important that the translational side is also part of the discussion,” says Simon. Like many in the GSA community, she has a particular interest in rare diseases. Gene therapy is the only true cure for many of these diseases, she says.

“If we are to stand a chance of being successful, we’ll need all hands on deck.”

 

Learn more about the Industry Sessions at TAGC ≫

Learn more about ways to connect with potential colleagues and employers at TAGC ≫

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